Determining the Pathogenicity of Autoantibodies in Idiopathic Small Fiber Neuropathy

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Grant Year

ANF Development Grant

Grant Type

Alexander Chamessian, MD, PhD


Washington University School of Medicine, St. Louis, MO


Project Summary

Small fiber neuropathy (SFN) is a group of disorders that involves preferential damage to and dysfunction of small diameter sensory and autonomic nerve fibers. There are many known causes of SFN, including diabetes, nutritional deficiencies, and certain autoimmune diseases. However, in many patients, the cause of SFN is never identified. Those cases are labeled “idiopathic” or “cryptogenic,” meaning the cause is unknown. The goal of this project is the determine the role of some of the SFN-associated autoantibodies. 

  • Up to $50,000 for up to 2 years. Total award $100,000 including indirect costs.
  • Complimentary AANEM Annual Meeting registration in the year the research is presented. This travel award does not need to be included in the grant application. It is paid above in the $50,000 award.
  • Complimentary AANEM membership during funding.

"I sincerely believe that our work will ultimately lead to real, substantial benefits to patients with SFN, which makes all the hard work ahead totally worth it."

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